Background and objectives Dementia prevalence continues to rise. It is therefore essential to provide feasible and effective recommendations to encourage healthy brain ageing and reduce dementia risk across the population. Appropriate nutrition represents a potential strategy to mitigate dementia risk and could be recommended by clinicians as part of mid-life health checks and other health initiatives to reduce dementia prevalence. The purpose of this review is to provide a clinician-focused update on the current state of the knowledge on nutrition and dementia prevention. Methods Narrative review. Results Strong evidence exists to support the consumption of healthy, plant-based dietary patterns (e.g. Mediterranean, MIND or Nordic diet) for maintaining cognitive function and reducing dementia risk in later life and is supported by dementia prevention guideline from leading public health bodies (e.g. World Health Organization). Emerging evidence suggests potential cognitive benefits of consuming specific nutrients/foods (e.g. n-3 fatty acids or fish, flavonols and B-vitamins) and multi-nutrient compounds (e.g. Fortasyn Connect). Challenges and opportunities for integrating nutritional/dietary interventions for dementia prevention into clinical practice are explored in this review. Conclusions Appropriate nutrition represents an important factor to help facilitate healthy cognitive ageing and allay dementia risk. The information provided in this article can help clinicians provide informed opinions on appropriate nutritional strategies as part of mid-life Health Checks and other risk reduction initiatives.

中文翻译：

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预防痴呆症的营养：临床医生的最新更新


背景和目标 痴呆症患病率持续上升。因此，有必要提供可行且有效的建议，以鼓励大脑健康老化并降低人群患痴呆症的风险。适当的营养是降低痴呆症风险的潜在策略，临床医生可以建议将其作为中年健康检查和其他降低痴呆症患病率的健康举措的一部分。本次综述的目的是提供以临床医生为中心的营养和痴呆症预防知识现状的最新信息。方法 叙述性回顾。结果 存在强有力的证据支持健康的植物性饮食模式（例如地中海饮食、MIND 饮食或北欧饮食）可维持认知功能并降低晚年痴呆风险，并得到主要公共卫生机构（例如世界卫生组织）的痴呆预防指南的支持。世界卫生组织）。新出现的证据表明，食用特定营养素/食物（例如 n-3 脂肪酸或鱼、黄酮醇和 B 族维生素）和多营养素化合物（例如 Fortasyn Connect）具有潜在的认知益处。本综述探讨了将预防痴呆症的营养/饮食干预措施纳入临床实践的挑战和机遇。结论 适当的营养是帮助促进健康认知衰老和降低痴呆风险的重要因素。本文提供的信息可以帮助临床医生就适当的营养策略提供明智的意见，作为中年健康检查和其他风险降低举措的一部分。