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Estimates of SARS-CoV-2 Hospitalization and Fatality Rates in the Prevaccination Period, United States
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2024-05-14 , DOI: 10.3201/eid3006.231285
Isabel Griffin , Jessica King , B. Casey Lyons , Alyson L. Singleton , Xidong Deng , Beau B. Bruce , Patricia M. Griffin

Few precise estimates of hospitalization and fatality rates from COVID-19 exist for naive populations, especially within demographic subgroups. We estimated rates among persons with SARS-CoV-2 infection in the United States during May 1–December 1, 2020, before vaccines became available. Both rates generally increased with age; fatality rates were highest for persons >85 years of age (24%) and lowest for children 1–14 years of age (0.01%). Age-adjusted case hospitalization rates were highest for African American or Black, not Hispanic persons (14%), and case-fatality rates were highest for Asian or Pacific Islander, not Hispanic persons (4.4%). Eighteen percent of hospitalized patients and 44.2% of those admitted to an intensive care unit died. Male patients had higher hospitalization (6.2% vs. 5.2%) and fatality rates (1.9% vs. 1.5%) than female patients. These findings highlight the importance of collecting surveillance data to devise appropriate control measures for persons in underserved racial/ethnic groups and older adults.



中文翻译:

美国疫苗接种前期间 SARS-CoV-2 住院率和死亡率的估计

对于幼稚人群,特别是在人口亚组中,目前对 COVID-19 住院率和死亡率的精确估计很少。我们估计了 2020 年 5 月 1 日至 12 月 1 日期间(疫苗问世之前)美国 SARS-CoV-2 感染者的感染率。这两种比率通常都随着年龄的增长而增加; 85 岁以上人群死亡率最高(24%),1-14 岁儿童死亡率最低(0.01%)。按年龄调整的病例住院率最高的是非裔美国人或黑人,而非西班牙裔人 (14%),病死率最高的是亚裔或太平洋岛民,而非西班牙裔人 (4.4%)。 18% 的住院患者和 44.2% 入住重症监护室的患者死亡。男性患者的住院率(6.2% vs. 5.2%)和病死率(1.9% vs. 1.5%)高于女性患者。这些发现凸显了收集监测数据的重要性,以便为服务不足的种族/族裔群体和老年人制定适当的控制措施。

更新日期:2024-05-15
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