当前位置: X-MOL 学术J. Org. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Photoredox Synthesis of Silicon-Containing Isoindolin-1-ones and Deuterated Analogues Through Hydrosilylation and Deuterium-silylation
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2024-05-10 , DOI: 10.1021/acs.joc.4c00576
Guo-Qin Wang 1 , Yue Zhang 1 , Yuan-Xia Zhou 1 , Dan Yang 1 , Pan Han 1 , Lin-Hai Jing 1 , Kai Tang 2
Affiliation  

An efficient, practical, and metal-free protocol for the synthesis of silicon-containing isoindolin-1-ones and deuterated analogues via the synergistic combination of an organic photoredox and hydrogen atom transfer process is described. This strategy features mild reaction conditions, high atom economy, and excellent functional group compatibility, delivering a myriad of structurally diverse and valuable products with good to excellent yields.

中文翻译:

通过氢化硅烷化和氘硅烷化光氧化还原合成含硅异吲哚啉-1-酮和氘代类似物

描述了一种通过有机光氧化还原和氢原子转移过程的协同组合合成含硅异吲哚啉-1-酮和氘代类似物的高效、实用且无金属的方案。该策略具有温和的反应条件、高原子经济性和优异的官能团相容性,可产生大量结构多样且有价值的产品,并具有良好的收率。
更新日期:2024-05-13
down
wechat
bug