Spatial transcriptomic analysis reveals local effects of intratumoral fusobacterial infection on DNA damage and immune signaling in rectal cancer,Gut Microbes

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Spatial transcriptomic analysis reveals local effects of intratumoral fusobacterial infection on DNA damage and immune signaling in rectal cancer
Gut Microbes ( IF 12.2 ) Pub Date : 2024-05-06 , DOI: 10.1080/19490976.2024.2350149
William P. Duggan _{1,

2,

3} , Batuhan Kisakol _{2,

3} , Ina Woods ₂ , Mohammedreza Azimi _{2,

3} , Heiko Dussmann _{2,

3} , Joanna Fay ₄ , Tony O’Grady ₄ , Barry Maguire _{1,

2,

3} , Ian S. Reynolds _{1,

2,

3} , Manuela Salvucci _{2,

3} , Daniel J. Slade ₅ , Deborah A. McNamara ₁ , John P. Burke ₁ , Jochen H.M. Prehn _{2,

3}

Affiliation

Mucinous colorectal cancer (CRC) is a common histological subtype of colorectal adenocarcinoma, associated with a poor response to chemoradiotherapy. The commensal facultative anaerobes fusobacteri...

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