Ultrahigh-molecular-weight polyethylene (UHMWPE), with its excellent wear resistance and biocompatibility, has important application as artificial joints. The most commonly used method to improve its wear resistance is to introduce crosslinking through irradiation. However, free radicals are introduced after radiation, which are easy to cause inflammation in the human body. Some antioxidants, such as vitamin E (), need to be added. However, the addition of could reduce the crosslinking density of UHMWPE and worsen the wear resistance of the material. Therefore, obtaining new antioxidants that could eliminate free radicals without affecting or even improving the crosslinking density of materials during irradiation is an important subject worth exploring. In this paper, a kind of natural polyphenol substance, resveratrol (RSV), was introduced as a new antioxidant and crosslinking promoter during irradiation crosslinking of UHMWPE. RSV can better eliminate free radicals than and further improve the crosslinking density to obtain UHMWPE materials with excellent oxidation resistance and high wear resistance. The multi-active phenolic hydroxyl structure of RSV molecule provides its free-radical trapping ability, and the appropriate molecular size of RSV may promote the -type crosslinking of UHMWPE, thereby increasing the crosslinking density. This work provides a new pathway for developing high-performance artificial joint prosthesis materials.

中文翻译：

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通过添加天然多酚抗氧化剂同时增强 UHMWPE 模压塑料的抗氧化性和耐磨性


超高分子量聚乙烯（UHMWPE）以其优异的耐磨性和生物相容性，在人工关节方面有着重要的应用。提高其耐磨性最常用的方法是通过辐照引入交联。但辐射后会引入自由基，容易引起人体内炎症。需要补充一些抗氧化剂，如维生素E（）。然而，添加会降低UHMWPE的交联密度，使材料的耐磨性变差。因此，获得能够消除自由基而不影响甚至提高材料在辐照过程中交联密度的新型抗氧化剂是一个值得探索的重要课题。本文引入一种天然多酚物质白藜芦醇(RSV)作为UHMWPE辐照交联过程中的新型抗氧化剂和交联促进剂。 RSV可以更好地消除自由基，并进一步提高交联密度，从而获得具有优异抗氧化性和高耐磨性的UHMWPE材料。 RSV分子的多活性酚羟基结构提供了其自由基捕获能力，适当的RSV分子大小可以促进UHMWPE的α型交联，从而提高交联密度。该工作为开发高性能人工关节假体材料提供了新途径。