AimTo evaluate the changes in periodontal parameters (reduction in probing pocket depth [PPD], gain in clinical attachment level [CAL] and reduction in full‐mouth bleeding on probing [BoP]) after subgingival instrumentation of periodontal pockets at different time points in systemically healthy patients suffering from periodontitis.Materials and MethodsFour databases were searched for RCTs that carried out subgingival instrumentation in periodontal pockets and evaluated PPD at a minimum of two consecutive time points other than baseline. The analysis was conducted for both all pocket depths and stratified for initially shallow (4–5 mm) and deep (≥6 mm) pockets and data were extracted for various time points, 1–2, 3–4 and 5–6 months. Weighted mean effects (WMEs) were calculated with 95% confidence interval (CI) and predictive intervals were calculated.ResultsTwenty‐nine RCTs were identified, and all of them were included in the meta‐analysis. The results showed that for both shallow and deep pockets there was a small though clinically meaningful change between 1‐ to 2‐month and 3‐ to 4‐month time points and between these and 5–6 months.ConclusionsIn systemically healthy patients, the greater part of reduction in PPD and gain in CAL occurs within the first 1–2 months after subgingival instrumentation. However, additional benefits in terms of pocket depth reduction occur beyond these early time points.

中文翻译：

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龈下器械治疗牙周炎后临床参数的变化以及牙周再评估的时机：系统评价和荟萃分析

目的 系统评价不同时间点牙周袋龈下器械固定后牙周参数的变化（探诊深度的减少[PPD]、临床附着水平的增加[CAL]和探诊时全口出血的减少[BoP]）患有牙周炎的健康患者。材料和方法在四个数据库中搜索了在牙周袋中进行龈下器械的随机对照试验，并在基线以外的至少两个连续时间点评估 PPD。对所有口袋深度进行分析，并对最初浅（4-5 mm）和深（≥6 mm）的口袋进行分层，并提取不同时间点（1-2、3-4 和 5-6 个月）的数据。加权平均效应（WME）以95％置信区间（CI）计算，并计算预测区间。结果确定了29个RCT，所有这些都纳入荟萃分析。结果显示，对于浅口袋和深口袋，在 1 至 2 个月和 3 至 4 个月的时间点以及这些时间点和 5-6 个月之间，存在微小但具有临床意义的变化。 结论 在全身健康的患者中， PPD 的部分减少和 CAL 的增加发生在龈下器械植入后的前 1-2 个月内。然而，在这些早期时间点之外，还出现了在减少袋深度方面的额外好处。