Human gut-associated Bifidobacterium species salvage exogenous indole, a uremic toxin precursor, to synthesize indole-3-lactic acid via tryptophan,Gut Microbes

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Human gut-associated Bifidobacterium species salvage exogenous indole, a uremic toxin precursor, to synthesize indole-3-lactic acid via tryptophan
Gut Microbes ( IF 12.2 ) Pub Date : 2024-05-05 , DOI: 10.1080/19490976.2024.2347728
Cheng Chung Yong ₁ , Takuma Sakurai ₁ , Hiroki Kaneko ₁ , Ayako Horigome ₁ , Eri Mitsuyama ₁ , Aruto Nakajima ₂ , Toshihiko Katoh ₂ , Mikiyasu Sakanaka ₂ , Takaaki Abe ₃ , Jin-Zhong Xiao ₁ , Miyuki Tanaka ₁ , Toshitaka Odamaki _{1,

2} , Takane Katayama ₂

Affiliation

Indole in the gut is formed from dietary tryptophan by a bacterial tryptophan-indole lyase. Indole not only triggers biofilm formation and antibiotic resistance in gut microbes but also contributes...

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