It is critical to explore intervenable environmental factors in suicide mortality. Based on 30,688 suicide cases obtained from the Mortality Surveillance System of the Jiangsu Provincial Centre for Disease Control and Prevention, we utilized a case-crossover design, and found that the OR of suicide deaths increased by a maximum of 0.71 % (95 % CI: 0.09 %, 1.32 %), 0.68 % (95 % CI: 0.12 %, 1.25 %), 0.77 % (95 % CI: 0.19 %, 1.37 %), 2.95 % (95 % CI: 1.62 %, 4.29 %), 4.18 % (95 % CI: 1.55 %, 6.88 %), and 0.93 % (95 % CI: 0.10 %, 1.77 %), respectively, for per 10 μg/m increase in the particulate matter (PM) with diameters ≤ 2.5 µm (PM), PM with diameters ≤ 10 µm (PM), ozone (O), nitrogen dioxide (NO), sulfur dioxide (SO), and per 0.1 mg/m increase in carbon monoxide (CO) concentrations with the conditional logistic regression analysis. People living in county-level cities were more susceptible. Particularly, a significant positive association was found between air pollutant mixture exposure and suicide deaths (OR=1.04,95 % CI: 1.01, 1.06). The excess fraction of suicide deaths due to air pollution reached a maximum of 8.07 %. In conclusion, we found associations between individual and mixed ambient air pollutants and suicide deaths, informing the development of integrated air pollution management and targeted measures for suicide prevention and intervention. As a major contributor to the global burden of disease, air pollution was confirmed by accumulating studies to have adverse impact on mental health, and potentially lead to suicide deaths. However, systematic studies on the association between air pollution and suicide mortality are lacking. We explored the associations of multiple air pollutants and pollution mixtures with suicide deaths and assessed excess suicide mortality due to air pollution, emphasizing the importance of air pollution control on suicide prevention. Our study provides evidence to support mechanistic studies on the association between air pollution and suicide, and informs comprehensive air pollution management.

中文翻译：

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单独和混合环境空气污染物对自杀死亡率的短期影响：案例交叉研究


探索自杀死亡率中可干预的环境因素至关重要。基于江苏省疾病预防控制中心死亡监测系统获得的30,688例自杀病例，我们采用病例交叉设计，发现自杀死亡的OR最多增加了0.71%（95% CI： 0.09%, 1.32%), 0.68% (95% CI: 0.12%, 1.25%), 0.77% (95% CI: 0.19%, 1.37%), 2.95% (95% CI: 1.62%, 4.29%), 4.18直径 ≤ 2.5 µm 的颗粒物 (PM) 每增加 10 µg/m，分别为 %（95 % CI：1.55 %、6.88 %）和 0.93 %（95 % CI：0.10 %、1.77 %）（ PM)、直径 ≤ 10 µm (PM)、臭氧 (O)、二氧化氮 (NO)、二氧化硫 (SO) 以及一氧化碳 (CO) 浓度每增加 0.1 mg/m，通过条件逻辑回归分析。居住在县级城市的人们更容易受到影响。特别是，空气污染物混合物暴露与自杀死亡之间存在显着正相关（OR=1.04，95% CI：1.01，1.06）。空气污染导致的自杀死亡超额比例最高达到8.07%。总之，我们发现单独和混合环境空气污染物与自杀死亡之间存在关联，为综合空气污染管理和自杀预防和干预的针对性措施的发展提供了信息。作为全球疾病负担的一个主要因素，越来越多的研究证实空气污染会对心理健康产生不利影响，并可能导致自杀死亡。然而，缺乏关于空气污染与自杀死亡率之间关系的系统研究。 我们探讨了多种空气污染物和污染混合物与自杀死亡的关联，并评估了空气污染导致的超额自杀死亡率，强调了空气污染控制对预防自杀的重要性。我们的研究为支持空气污染与自杀之间关联的机制研究提供了证据，并为全面的空气污染管理提供了信息。