The peptide hormone adropin, which is downregulated in dermal fibroblasts in patients with systemic sclerosis (SSc), inhibits TGFβ-mediated fibrosis in in vitro and ex vivo models of human skin, and has potential for the treatment of SSc.

中文翻译：

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Adropin 抑制 SSc 纤维化

肽类激素 adropin 在系统性硬化症 (SSc) 患者的真皮成纤维细胞中表达下调，在体外和离体人体皮肤模型中抑制 TGFβ 介导的纤维化，具有治疗 SSc 的潜力。