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Rifampicin has no role in treatment of Mycobacterium avium complex pulmonary disease and bactericidal sterilising drugs are needed: a viewpoint
European Respiratory Journal ( IF 24.3 ) Pub Date : 2024-05-02 , DOI: 10.1183/13993003.02210-2023
Jakko van Ingen , Wouter Hoefsloot , Véronique Dartois , Thomas Dick

Extract

Current rifampicin/ethambutol/azithromycin regimens for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD) are long, toxic and yield relatively poor outcomes [1]: a meta-analysis lumping nodular bronchiectatic disease and fibro-cavitary disease reported a 65% prolonged culture conversion rate; following initially successful treatment, recurrence rates of 30% have been reported [2].



中文翻译:

利福平治疗鸟分枝杆菌复合型肺病无作用需杀菌消毒药物:一个观点

提炼

目前用于治疗鸟分枝杆菌复合型肺病 (MAC-PD) 的利福平/乙胺丁醇/阿奇霉素方案时间长、毒性大且疗效相对较差 [1]:一项将结节性支气管扩张病和纤维空洞病合并的荟萃分析报告称 65 %延长的培养物转化率;据报道,在最初成功治疗后,复发率为 30% [2]。

更新日期:2024-05-02
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