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Diamond-Like Carbon Depositing on the Surface of Polylactide Membrane for Prevention of Adhesion Formation During Tendon Repair
Nano-Micro Letters ( IF 26.6 ) Pub Date : 2024-04-30 , DOI: 10.1007/s40820-024-01392-7 Yao Xiao , Zaijin Tao , Yufeng Ju , Xiaolu Huang , Xinshu Zhang , Xiaonan Liu , Pavel A. Volotovski , Chao Huang , Hongqi Chen , Yaozhong Zhang , Shen Liu
中文翻译:
聚丙交酯膜表面沉积类金刚石碳以防止肌腱修复过程中粘连的形成
更新日期:2024-04-30
Nano-Micro Letters ( IF 26.6 ) Pub Date : 2024-04-30 , DOI: 10.1007/s40820-024-01392-7 Yao Xiao , Zaijin Tao , Yufeng Ju , Xiaolu Huang , Xinshu Zhang , Xiaonan Liu , Pavel A. Volotovski , Chao Huang , Hongqi Chen , Yaozhong Zhang , Shen Liu
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The anti-adhesion effect of polylactic acid (PLA) membrane with diamond-like carbon (DLC) depositing is 44.72%, enhanced by 23.11% compared to PLA.
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DLC deposited on PLA membranes has been shown to effectively reduce the levels of reactive oxygen species, leading to a decrease in the expression of pro-inflammatory cytokines within peritendinous adhesion tissue.
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DLC decelerates PLA biodegradation and lactic production, which reduces the number of CD68+CD206+ macrophages within peritendinous adhesion tissue.
中文翻译:
聚丙交酯膜表面沉积类金刚石碳以防止肌腱修复过程中粘连的形成
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沉积类金刚石碳(DLC)的聚乳酸(PLA)膜的抗粘连效果为44.72%,比PLA提高了23.11%。
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沉积在 PLA 膜上的 DLC 已被证明可以有效降低活性氧的水平,从而导致腱周粘连组织内促炎细胞因子的表达减少。
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DLC 减缓 PLA 生物降解和乳酸产生,从而减少腱周粘连组织内CD68 + CD206 +巨噬细胞的数量。