Chiral heterocyclic compounds play a crucial role in the pharmaceutical science, materials science, and agrochemical industries. The critical step for synthesizing chiral heterocycles is the formation of asymmetric carbon‐heteroatom bonds, which can be achieved in a chiral environment under thermal or photochemical conditions. However, photochemical asymmetric transformation has become an area of immense growth in the past 15 years. In the drug discovery and development era, chiral photochemical transformations have drawn the attention of researchers to develop new synthetic strategies for chiral heterocycles via asymmetric carbon‐heteroatom bond formation. Chiral photochemistry in the pathway of asymmetric synthesis requires a chirality source which is transferred to the products. A catalytic chiral metal complexing agent or a chiral photosensitizer that generally follows a single electron transfer (SET) or oxidative and reductive quenching cycle has been widely exploited to achieve this goal. In this review, we have demonstrated the recent development of photochemical synthesis of chiral heterocycles via asymmetric carbon‐heteroatom bond formation by using a chiral metal catalyst, asymmetric organocatalyst, or dual catalytic system based on their plausible mechanism.

中文翻译：

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通过不对称碳杂原子键形成手性杂环的光化学合成

手性杂环化合物在制药科学、材料科学和农化工业中发挥着至关重要的作用。合成手性杂环的关键步骤是形成不对称碳杂原子键，这可以在热或光化学条件下的手性环境中实现。然而，光化学不对称转化在过去 15 年中已成为一个巨大增长的领域。在药物发现和开发时代，手性光化学转化引起了研究人员的关注，通过不对称碳杂原子键的形成来开发手性杂环的新合成策略。不对称合成途径中的手性光化学需要将手性源转移到产物中。通常遵循单电子转移（SET）或氧化和还原猝灭循环的催化手性金属络合剂或手性光敏剂已被广泛用于实现这一目标。在这篇综述中，我们基于其合理的机理，展示了使用手性金属催化剂、不对称有机催化剂或双催化系统通过不对称碳-杂原子键形成手性杂环的光化学合成的最新进展。