The female reproductive tract undergoes dynamic changes across the life span. Congenital abnormalities, life events, and medical interventions can negatively affect the structure and function of reproductive tract organs, resulting in lifelong sequelae. The objective of regenerative gynecology is to discover and promote endogenous mechanisms by which a healthy tissue maintains overall tissue integrity after injury, after disease, or with age. In this review, we discuss some of the key state-of-the-art cell-based and scaffolding therapies that have been applied to regenerate gynecologic tissues and organs primarily in animal and tissue culture models. We further discuss the limitations of current technologies, problems of implementation and scalability, and future outlook of the field.

中文翻译：

---

妇科再生医学。

女性生殖道在一生中经历动态变化。先天性异常、生活事件和医疗干预会对生殖道器官的结构和功能产生负面影响，导致终生后遗症。再生妇科的目标是发现和促进健康组织在受伤、疾病或年龄增长后维持整体组织完整性的内源机制。在这篇综述中，我们讨论了一些最先进的基于细胞和支架的疗法，这些疗法主要在动物和组织培养模型中用于再生妇科组织和器官。我们进一步讨论了当前技术的局限性、实施和可扩展性问题以及该领域的未来前景。