Over the past decade, considerable progress has been made in the control, elimination, and eradication of neglected tropical diseases (NTDs). Despite these advances, most NTD programs have recently experienced important setbacks; for example, NTD interventions were some of the most frequently and severely impacted by service disruptions due to the coronavirus disease 2019 (COVID-19) pandemic. Mathematical modeling can help inform selection of interventions to meet the targets set out in the NTD road map 2021–2030, and such studies should prioritize questions that are relevant for decision-makers, especially those designing, implementing, and evaluating national and subnational programs. In September 2022, the World Health Organization hosted a stakeholder meeting to identify such priority modeling questions across a range of NTDs and to consider how modeling could inform local decision making. Here, we summarize the outputs of the meeting, highlight common themes in the questions being asked, and discuss how quantitative modeling can support programmatic decisions that may accelerate progress towards the 2030 targets.

中文翻译：

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加快实现 2030 年被忽视的热带病目标：定量模型如何支持规划决策？

在过去的十年中，在控制、消除和根除被忽视的热带病（NTD）方面取得了相当大的进展。尽管取得了这些进步，大多数 NTD 项目最近都经历了重大挫折。例如，NTD 干预措施是受 2019 年冠状病毒病 (COVID-19) 大流行造成的服务中断影响最频繁、影响最严重的干预措施之一。数学模型可以帮助选择干预措施，以实现 2021-2030 年 NTD 路线图设定的目标，此类研究应优先考虑与决策者相关的问题，特别是那些设计、实施和评估国家和地方项目的决策者。 2022 年 9 月，世界卫生组织主办了一次利益相关者会议，以确定一系列 NTD 中的此类优先建模问题，并考虑建模如何为当地决策提供信息。在这里，我们总结了会议的成果，强调了所提出问题中的共同主题，并讨论了定量模型如何支持可能加速实现 2030 年目标进展的计划性决策。