Photobiocatalysis has emerged as a powerful tool in organic synthesis because the integrated technology blends the complementary advantages of the two distinct catalytic subdisciplines. More important, photobiocatalysis holds great promise for green manufacturing of various chemicals, materials, and fuels. In this perspective, we summarize recent impressive developments in photobiocatalysis, ranging from parallel/linear photobiocatalytic cascades and light-assisted biotransformations to synergistic photoenzymatic catalysis, and discuss the major limitations. In addition, multicatalytic processes beyond photobiocatalysis are highlighted, and an outlook on future research directions is proposed.

光生物催化已成为有机合成中的强大工具，因为集成技术融合了两个不同催化分支学科的互补优势。更重要的是，光生物催化对于各种化学品、材料和燃料的绿色制造具有广阔的前景。从这个角度来看，我们总结了光生物催化领域最近令人印象深刻的进展，从平行/线性光生物催化级联和光辅助生物转化到协同光酶催化，并讨论了主要局限性。此外，还强调了光生物催化之外的多重催化过程，并提出了对未来研究方向的展望。