Combined immune checkpoint blockade (ICB) for cancer exhibits good efficacy in a subset of patients but also associates with immune-related adverse events. Xue et al. use an elegant drug screening strategy to identify the antimicrobial drug clofazimine as an agent that both potentiates ICB efficacy and decreases immune-related adverse events.

中文翻译：

---

吃完蛋糕就吃它吗？氯法齐明增强免疫治疗同时限制副作用

联合免疫检查点阻断（ICB）治疗癌症在一部分患者中表现出良好的疗效，但也与免疫相关的不良事件有关。薛等人。使用优雅的药物筛选策略来鉴定抗菌药物氯法齐明作为一种既能增强 ICB 疗效又能减少免疫相关不良事件的药物。