ObjectivesThis RCT aimed to compare zirconia and titanium dental implants in the maxillary premolar region. The comparison was based on marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs) 1 year after prosthetic loading.Materials and MethodsFifty patients were randomly assigned to receive either a zirconia (ZrO2, n = 25) implant or a titanium (Ti, n = 25) bone‐level implant. Implants were provided with a lithium disilicate crown 3 months after placement. Follow‐up was at 1 month and after 1 year. The primary outcome pertained to changes in MBL. Reported secondary outcomes consisted of implant survival, peri‐implant tissue health, aesthetics, and PROMs.ResultsMean MBL change after 1 year was 0.01 mm (SD = 0.45; min = 0.72, max = 0.86) for ZrO2 and −0.09 mm (SD = 0.34; min = 0.53, max = −1.06) for Ti (p = .439). Scores for the other clinical outcome parameters and PROMs were generally favorable, with no significant differences. However, significant differences were found for the aesthetic outcomes regarding two criteria: (a) level of facial mucosa (p = .022), in favor of Ti, and (b) root convexity/soft tissue color and texture (p = .005) in favor of ZrO2.Conclusion and clinical implicationsThe ZrO2 and Ti implant types used in this study, replacing a single missing maxillary premolar, show a comparable outcome in terms of MBL change after 1 year. Clinical and aesthetic parameters, as well as PROMs, are favorable and similar between both implant types after 1 year of prosthetic loading. These short‐term study results suggest that both are suitable for clinical use.

中文翻译：

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上颌单牙替换中氧化锆与钛种植体的随机临床试验

目的该随机对照试验旨在比较上颌前磨牙区域的氧化锆和钛牙种植体。比较基于假体装载后 1 年后边缘骨水平 (MBL) 变化、临床参数、美观结果和患者相关结果测量 (PROM)。 材料和方法 50 名患者被随机分配接受氧化锆 (ZrO2) 治疗2,n= 25) 植入物或钛 (Ti,n= 25) 骨水平种植体。植入后 3 个月，为种植体提供二硅酸锂牙冠。随访时间为 1 个月和 1 年后。主要结果与 MBL 的变化有关。报告的次要结局包括种植体存活、种植体周围组织健康、美观和 PROM。结果 ZrO 1 年后平均 MBL 变化为 0.01 毫米（SD = 0.45；最小值 = 0.72，最大值 = 0.86）2对于 Ti (p =.439）。其他临床结果参数和 PROM 的评分总体良好，没有显着差异。然而，就两个标准而言，美学结果存在显着差异：（a）面部粘膜水平（p =.022），有利于 Ti，以及（b）根凸度/软组织颜色和纹理（p =.005) 有利于 ZrO2结论及临床意义ZrO2本研究中使用的 Ti 种植体类型替代了单个缺失的上颌前磨牙，在 1 年后的 MBL 变化方面显示出可比的结果。经过一年的假体负载后，两种种植体类型的临床和美学参数以及 PROM 均良好且相似。这些短期研究结果表明两者都适合临床使用。