The EAACI Guidelines on the impact of short‐term exposure to outdoor pollutants on asthma‐related outcomes provide recommendations for prevention, patient care and mitigation in a framework supporting rational decisions for healthcare professionals and patients to individualize and improve asthma management and for policymakers and regulators as an evidence‐informed reference to help setting legally binding standards and goals for outdoor air quality at international, national and local levels. The Guideline was developed using the GRADE approach and evaluated outdoor pollutants referenced in the current Air Quality Guideline of the World Health Organization as single or mixed pollutants and outdoor pesticides. Short‐term exposure to all pollutants evaluated increases the risk of asthma‐related adverse outcomes, especially hospital admissions and emergency department visits (moderate certainty of evidence at specific lag days). There is limited evidence for the impact of traffic‐related air pollution and outdoor pesticides exposure as well as for the interventions to reduce emissions. Due to the quality of evidence, conditional recommendations were formulated for all pollutants and for the interventions reducing outdoor air pollution. Asthma management counselled by the current EAACI guidelines can improve asthma‐related outcomes but global measures for clean air are needed to achieve significant impact.

中文翻译：

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EAACI 过敏和哮喘环境科学指南：短期暴露于室外空气污染物对哮喘相关结果的影响和缓解措施建议

关于短期接触室外污染物对哮喘相关结果的影响的 EAACI 指南在一个框架内提供了预防、患者护理和缓解的建议，支持医疗保健专业人员和患者做出合理决策，以实现个体化和改善哮喘管理，并为政策制定者和监管者提供支持作为有证据的参考，帮助在国际、国家和地方层面制定具有法律约束力的室外空气质量标准和目标。该指南采用GRADE方法制定，并对世界卫生组织现行空气质量指南中提到的室外污染物作为单一或混合污染物和室外杀虫剂进行了评估。短期接触所有评估的污染物会增加哮喘相关不良后果的风险，特别是入院和急诊科就诊（特定滞后天的证据质量中等）。关于与交通相关的空气污染和户外农药暴露的影响以及减少排放的干预措施的证据有限。由于证据的质量，针对所有污染物和减少室外空气污染的干预措施制定了有条件的建议。当前 EAACI 指南建议的哮喘管理可以改善哮喘相关结果，但需要采取全球清洁空气措施才能取得重大影响。