Vaginal dryness is an important factor influencing sexual function in women with primary Sjögren's syndrome (pSS). Previous studies showed a higher degree of inflammation in vaginal biopsies from pSS patients compared to non-pSS controls. However, the molecular pathways that drive this inflammation remain unclear. Therefore, the aim of this study was to investigate inflammatory pathway activity in pSS patients' vaginal tissue.

中文翻译：

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原发性干燥综合征患者阴道组织中干扰素信号增加。

阴道干燥是影响原发性干燥综合征（pSS）女性性功能的重要因素。先前的研究表明，与非 pSS 对照相比，pSS 患者的阴道活检中炎症程度更高。然而，驱动这种炎症的分子途径仍不清楚。因此，本研究的目的是调查 pSS 患者阴道组织中的炎症通路活性。