Over the past decade, global reports have shown a rise in the harmful effects of microplastics (MPs) on marine fish. This study analysed marine species' biochemical biomarker responses to microplastic exposure, finding that MPs can induce oxidative stress in marine fish through meta-regression results. Overall, exposure to MPs resulted in the activation of antioxidant defence mechanisms, such as superoxide dismutase, catalase and glutathione reductase, detoxification enzymes such as glutathione-S-transferase, the detection of malondialdehyde, and inhibition of acetylcholinesterase. Moreover, results highlight oxidative stress biomarkers were activated in wild species that had ingested MPs, indicating potential harm to marine fish, as confirmed in experimental studies. Furthermore, even though MPs’ exposure is better regulated in an experimental setting, it is challenging to replicate actual exposure and environmental factors. The study's findings show the need for more investigation into the hazardous consequences of exposure to environmental MPs on species surveyed in the maritime environment.

中文翻译：

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与海洋鱼类微塑料摄入相关的潜在生物标志物的荟萃分析

过去十年，全球报告显示微塑料 (MP) 对海洋鱼类的有害影响有所增加。这项研究分析了海洋物种对微塑料暴露的生化生物标志物反应，发现 MPs 可以通过荟萃回归结果诱导海洋鱼类的氧化应激。总体而言，接触 MP 会导致抗氧化防御机制的激活，例如超氧化物歧化酶、过氧化氢酶和谷胱甘肽还原酶、解毒酶（例如谷胱甘肽-S-转移酶）、丙二醛的检测以及乙酰胆碱酯酶的抑制。此外，结果强调，摄入 MP 的野生物种中氧化应激生物标志物被激活，这表明对海洋鱼类存在潜在危害，正如实验研究所证实的那样。此外，尽管议员的暴露在实验环境中得到了更好的监管，但复制实际暴露和环境因素仍然具有挑战性。该研究的结果表明，需要对海洋环境中调查的物种暴露于环境 MP 的危险后果进行更多调查。