AimThis study aimed to investigate the effects of diabetes care on periodontal inflammation.Materials and MethodsThis prospective cohort study included 51 Japanese patients with type 2 diabetes who underwent intensive diabetes care including educational hospitalization and regular outpatient treatment for 6 months. Dental prophylaxis without subgingival scaling was provided three times during the observational period. Associations between changes in periodontal parameters and glycaemic control levels were evaluated using multiple regression analysis.ResultsOverall, 33 participants (mean age: 58.7 ± 12.9) were followed up for 6 months. At baseline examination, 82% were diagnosed with Stage III or IV periodontitis. Haemoglobin A1c (HbA1c) level changed from 9.6 ± 1.8% at baseline to 7.4 ± 1.3% at 6 months. The ratio of probing pocket depth (PPD) ≥4 mm, bleeding on probing (BOP), full‐mouth plaque control record (PCR), periodontal epithelial surface area (PESA) and periodontal inflamed surface area (PISA) also significantly improved. The reduction in PPD and PESA was significantly associated with changes in both HbA1c and fasting plasma glucose (FPG) levels, and the reduction in PISA was significantly associated with an improvement in FPG after adjusting for smoking, change in body mass index and full‐mouth PCR.ConclusionsThis is the first study to report a significant improvement in PPD and BOP after intensive diabetes care and dental prophylaxis without subgingival scaling. Clinical trial registration number: UMIN000040218.

中文翻译：

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2 型糖尿病患者接受强化糖尿病护理和龈上牙科预防后牙周参数的改善：一项前瞻性队列研究

目的本研究旨在探讨糖尿病护理对牙周炎症的影响。材料和方法这项前瞻性队列研究纳入了 51 名日本 2 型糖尿病患者，他们接受了为期 6 个月的强化糖尿病护理，包括教育住院治疗和常规门诊治疗。在观察期间，进行了 3 次不进行龈下洁治的牙科预防治疗。使用多元回归分析评估牙周参数变化与血糖控制水平之间的关联。结果总体而言，33 名参与者（平均年龄：58.7 ± 12.9）接受了 6 个月的随访。在基线检查中，82% 的人被诊断患有 III 期或 IV 期牙周炎。A1c 血红蛋白 (HbA1c) 水平从基线时的 9.6 ± 1.8% 变为 6 个月时的 7.4 ± 1.3%。探诊袋深度（PPD）≥4毫米的比率、探诊出血（BOP）、全口菌斑控制记录（PCR）、牙周上皮表面积（PESA）和牙周炎症表面积（PISA）也显着改善。PPD 和 PESA 的降低与 HbA1c 和空腹血糖 (FPG) 水平的变化显着相关，并且在调整吸烟、体重指数和满口变化后，PISA 的降低与 FPG 的改善显着相关。 PCR.结论这是第一项报告在未进行龈下洗牙的情况下进行糖尿病强化护理和牙科预防后 PPD 和 BOP 显着改善的研究。临床试验注册号：UMIN000040218。