In this issue of The Journal of Rheumatology, Fairley and colleagues investigated the effects of concomitant left ventricular diastolic dysfunction (LVDD) in a small cohort of patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) derived from the larger Australian Scleroderma Cohort Study.¹ Consistent with prior reports, the authors found that patients with SSc-ILD with LVDD experienced dyspnea and reduced survival. In addition, these patients were older, had longer SSc disease duration exceeding 6 years, received treatment with immunosuppressive drugs, and had additional cardiovascular (CV) comorbidities.

中文翻译：

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硬皮病探戈：揭开舒张功能障碍和间质性肺疾病的微妙之舞。

在本期《风湿病学杂志》中，Fairley 及其同事研究了一小群患有系统性硬化症 (SSc) 相关间质性肺疾病 (ILD) 的患者中伴随左心室舒张功能障碍 (LVDD) 的影响，这些患者源自较大的澳大利亚硬皮病队列研究。¹与之前的报告一致，作者发现患有 LVDD 的 SSc-ILD 患者会出现呼吸困难并降低生存率。此外，这些患者年龄较大，SSc 病程较长，超过 6 年，接受免疫抑制药物治疗，并有其他心血管 (CV) 合并症。