Survival and Quality of Life after Isolated Hepatic Perfusion with Melphalan as a Treatment for Uveal Melanoma Liver Metastases - Final Results from the Phase III Randomized Controlled Trial SCANDIUM.,Annals of Surgery

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Survival and Quality of Life after Isolated Hepatic Perfusion with Melphalan as a Treatment for Uveal Melanoma Liver Metastases - Final Results from the Phase III Randomized Controlled Trial SCANDIUM.
Annals of Surgery ( IF 9 ) Pub Date : 2024-02-29 , DOI: 10.1097/sla.0000000000006255
Roger Olofsson Bagge _{1,

2,

3} , Axel Nelson ₄ , Amir Shafazand _{3,

5} , Charlotta All-Eriksson ₆ , Christian Cahlin ₇ , Nils Elander ₈ , Anders Gustavsson _{9,

10} , Hildur Helgadottir ₁₁ , Jens Folke Kiilgaard ₁₂ , Sara Kinhult ₁₃ , Ingrid Ljuslinder ₁₄ , Jan Mattsson ₂ , Magnus Rizell ₇ , Malin Sternby Eilard ₇ , Gustav J. Ullenhag _{15,

16} , Jonas A. Nilsson _{1,

17} , Lars Ny ₄ , Per Lindnér ₇

Affiliation

Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden
Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden
Department of Radiology, Alingsås Hospital, Alingsås, Sweden
Department of Ophthalmology, Mölndal Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden
Transplant Institute, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden
Department of Oncology and Department of Clinical and Biomedical Sciences, Linköping University, Linköping, Sweden
Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Solna, Sweden
Quantify Research, Stockholm, Sweden
Department of Oncology, Karolinska University Hospital, Stockholm, Sweden
Department of Ophthalmology, Rigshospitalet, Copenhagen University Hospital Copenhagen, Denmark
Department of Oncology, Skåne University Hospital, Lund, Sweden
Department of Oncology, Norrlands University Hospital, Umeå, Sweden
Department of Immunology, Genetics and Pathology (IGP), Science for Life Laboratories, Uppsala University, Uppsala, Sweden
Department of Oncology, Uppsala University Hospital, Uppsala, Sweden
Harry Perkins Institute of Medical Research, University of Western Australia, Perth, WA, Australia

To investigate overall survival (OS) and health-related quality of life (HRQOL) of first-line isolated hepatic perfusion (IHP) compared to best alternative care (BAC) for patients with uveal melanoma liver metastases.

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