In this Tools of the Trade, Juliann Shih describes the development of BISCUT, which detects genomic loci that are subject to fitness advantages or disadvantages by interrogating the length distributions of partial somatic copy-number alterations to enable the discovery of new drivers of aneuploidy in cancer.

中文翻译：

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发现癌症非整倍体的新驱动因素

在这本行业工具中，Juliann Shih 描述了 BISCUT 的开发，该技术通过询问部分体细胞拷贝数改变的长度分布来检测受适应性优势或劣势影响的基因组位点，从而能够发现癌症非整倍性的新驱动因素。