Photocatalysis has emerged as a pivotal tool in organic synthesis, facilitating mild, environmentally friendly, and efficient transformations toward crucial molecular scaffolds. Within this realm, thermally activated delayed fluorescence (TADF) emitters are used in widespread applications in photocatalysis due to their numerous advantages. Notably, TADF photocatalysts have recently demonstrated substantial utility in realizing enantioselective and diastereoselective transformations with the practical construction of central or/and axial chirality. The successful integration of TADF photocatalysts, whether D-A type or Cu(I) complexes, with organic/inorganic additives or traditional metal catalysts, with or without the incorporation of a chiral source, has markedly broadened the scope of photocatalysis for chiral synthesis. This convergence has ushered in innovative synthetic strategies in the field. The primary focus of this review is to accentuate recent advancements in stereoselective transformations facilitated by TADF photocatalysts. Additionally, we aim to offer insights into the challenges and opportunities that lie ahead in this evolving domain.

光催化已成为有机合成的关键工具，促进温和、环保且高效的关键分子支架转化。在这一领域中，热激活延迟荧光（TADF）发射器由于其众多优点而在光催化领域得到广泛应用。值得注意的是，TADF光催化剂最近在通过中心或/和轴向手性的实际构建实现对映选择性和非对映选择性转化方面表现出巨大的实用性。 TADF光催化剂（无论是D-A型还是Cu(I)配合物）与有机/无机添加剂或传统金属催化剂（无论是否掺入手性源）的成功整合，显着拓宽了光催化手性合成的范围。这种融合催生了该领域的创新合成策略。本综述的主要重点是强调 TADF 光催化剂促进的立体选择性转化的最新进展。此外，我们的目标是深入了解这个不断发展的领域面临的挑战和机遇。