Myositis-associated autoantibodies (MAAs) have been associated with overlap myositis, certain disease manifestations such as interstitial lung disease (ILD), and worse prognosis in the idiopathic inflammatory myopathies. MAAs overall remain largely uncharacterized in patients with juvenile-onset myositis. Moreover, it is unknown whether the number of MAAs is associated with disease severity.

中文翻译：

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青少年肌炎患者的肌炎相关自身抗体与难治性疾病和死亡率相关


肌炎相关自身抗体（MAAs）与重叠性肌炎、某些疾病表现如间质性肺病（ILD）以及特发性炎症性肌病的预后较差有关。青少年发病的肌炎患者的 MAA 总体上仍然没有特征。此外，尚不清楚 MAA 的数量是否与疾病严重程度相关。