Since the report of diphenylalanine (FF) peptide self-assembly into discrete nanostructures in 2003, aromatic short peptide architectonics have been extensively studied globally and exhibiting tremendous application potentials in diverse fields. In this occasion of the 20th anniversary of the FF self-assembly nanotechnology, the key achievements in the development of bioinspired supramolecular peptide technology are comprehensively reviewed. In particular, we discuss self-organization of aromatic short peptides into low-dimensional dots moving on to ripening to diverse architectures and microfabrication into large-scale, highly-ordered arrays. Consequent optical, mechanical, electrical, catalytic and biomedical characteristics of these supramolecular architectures are also discussed. Challenges in aromatic short peptide architectonics are assessed and several perspectives for future exploitation are proposed.

自2003年报道二苯丙氨酸（FF ）肽自组装成离散纳米结构以来，芳香族短肽结构学在全球范围内得到了广泛的研究，并在各个领域展现出巨大的应用潜力。值此FF自组装纳米技术20周年之际，全面回顾仿生超分子肽技术发展的关键成果。特别是，我们讨论了芳香短肽自组织成低维点，进而成熟为不同的结构和微加工成大规模、高度有序的阵列。还讨论了这些超分子结构的光学、机械、电学、催化和生物医学特性。评估了芳香族短肽结构学的挑战，并提出了未来开发的几种观点。