Newly published European guidelines for the management of systemic lupus erythematosus (SLE) and lupus nephritis, specifically recommending early and aggressive use of new medications, signal that the old paradigm of SLE management is shifting. Although it presents challenges, this shift is welcome — and is likely to have far-reaching implications.

中文翻译：

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改变 SLE 管理模式：挑战和影响

新发布的欧洲系统性红斑狼疮 (SLE) 和狼疮性肾炎治疗指南特别建议早期积极使用新药物，这表明 SLE 治疗的旧模式正在发生转变。尽管带来了挑战，但这种转变是值得欢迎的，而且可能会产生深远的影响。